Vol 3, Issue 4
Pages 90–96
Published: 01 Oct 2020
Flanigan RC1, Dornbier R1, Quek ML1, Woods M1, Gorbonos A1, Gupta G1, Harkenrider MM2, Solanki A2, Badami A3, Henry E3, Berg S3, Bova D4, Barkan GA5, Picken MM5
Article Information
Citation: Flanigan RC, Dornbier R, Quek ML, Woods M, Gorbonos A, Gupta G, Harkenrider MM, Solanki A, Badami A, Henry E, Berg S, Bova D, Barkan GA, Picken MM. Penile Paget ’s Disease: A Case Report and Review of the Literature. Archives of Nephrology and Urology 3 (2020): 090-096.
DOI: 10.26502/anu.2644-2833025
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Abstract
Extramammary Paget’s Disease (EMPD) is a rare cutaneous, slow growing, intraepithelial adenocarcinoma that can be either primary (intraepithelial arising within the epidermis) or secondary (intraepithelial spread of a visceral carcinoma). Here we present the case of a 63-year-old male with EMPD of the glans penis stemming from underlying urothelial carcinoma. Our treatment decision elected for management with chemotherapy and local treatment with radiation therapy. Subsequent, review of the literature demonstrated a rare disease with a variety of underlying malignancies causing this secondary pathology. Caregivers should be aware of the association of Paget’s disease and urothelial cancer and should have a high index of suspicion that erythematous penile lesions may represent Paget’s disease and that penile biopsies should be performed early in this setting.
Keywords
Extramammary Paget’s Disease; Adenocarcinoma; Urothelial carcinoma
Article Details
1. Introduction