Vol 4, Issue 2
Pages 134–141
Published: 25 May 2021
Nabeel Hussain1, Zoia Akram2*, Chisa Okachi Oparanma3, Sheheryar Sharif4, Rubia Ali5, Fatima Ali Raza6, Tooba Shaukat Butt7, Belonwu Valentine Okafor8, Aswa Gondal9, Wilson Olaotan Vaughan3, Sadaf Munir10, Asma Nasir10, Syed Burhanuddin Khadri11, Muhammad Arslan Aslam12, Ghulam Muhammad Humayun2, Ogechi Lilian Okeke13
Article Information
Citation: Nabeel Hussain, Zoia Akram, Chisa Okachi Oparanma, Sheheryar Sharif, Rubia Ali, Fatima Ali Raza, Tooba Shaukat Butt, Abdul Habib Eimal Latif, Farukhzad Hafizyar, Wilson Olaotan Vaughan, Sadaf Munir, Asma Nasir, Syed Burhanuddin Khadri, Muhammad Arslan Aslam, Ghulam Muhammad Humayun, Ogechi Lilian Okeke. Role of NSAIDs in the Prevention of Post-ERCP Pancreatitis: A Narrative Review. Archives of Internal Medicine Research 4 (2021): 134-141.
DOI: 10.26502/aimr.0064
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Abstract
Acute pancreatitis is the most common complication after Endoscopic Retrograde Cholangio-Pancreatography (ERCP), occurring in about 3.5% of the procedures. NSAIDs have been shown to play a vital role in the prevention of post-endoscopic retrograde cholangio-pancreatography pancreatitis (PEP). How-ever, not much is known about the most effective drug in preventing this complication. Furthermore, there is a lot of conflict regarding the correct dose, route, and timing of the drug administration. The current study aims to investigate the role of NSAIDs in the prevention of PEP. The literature search was performed using PubMed, and after applying the inclusion and exclusion criteria, 9 published papers were found. All relevant articles on the topic have been included. Our review article has demonstrated that NSAIDs are quite effective in reducing the chances of PEP. It is best to administer drugs per-rectally and pre-procedurally for it to be more effective. However, more Randomized Controlled Trials (RCTs) need to be done to fully understand NSAIDs' role in PEP prophylaxis.
Keywords
Acute Pancreatitis, ERCP, NSAIDs
Acute Pancreatitis articles; ERCP articles; NSAIDs articles
Article Details
1. Introduction